Mechanisms of folate cofactors

Stephen J. Benkovic; Charles M. Tatum

doi:10.1016/0968-0004(77)90366-8

Mechanisms of folate cofactors

Stephen J. Benkovic, Charles M. Tatum

Chemistry

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Stereospecific isotopic substitution of hydrogen at the bridging carbon in 5,10-methylene tetrahydrofolate promises further insight into stereochemical events at the active site of several folate requiring enzymes.

Original language	English (US)
Pages (from-to)	161-163
Number of pages	3
Journal	Trends in Biochemical Sciences
Volume	2
Issue number	7
DOIs	https://doi.org/10.1016/0968-0004(77)90366-8
State	Published - Jul 1977

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology

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10.1016/0968-0004(77)90366-8

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@article{23bd9c71a9854106bd32bfe38a375850,

title = "Mechanisms of folate cofactors",

abstract = "Stereospecific isotopic substitution of hydrogen at the bridging carbon in 5,10-methylene tetrahydrofolate promises further insight into stereochemical events at the active site of several folate requiring enzymes.",

author = "Benkovic, {Stephen J.} and Tatum, {Charles M.}",

note = "Funding Information: This work was supported by research grants AM 09602 from the National Institute ofArthritis, Metabolism and Digestive Diseases, CA 10439 and CA 12226 from the National Cancer Institute, and GM 20594 from National Institute of General Medical Sciences.",

year = "1977",

month = jul,

doi = "10.1016/0968-0004(77)90366-8",

language = "English (US)",

volume = "2",

pages = "161--163",

journal = "Trends in Biochemical Sciences",

issn = "0968-0004",

publisher = "Elsevier Limited",

number = "7",

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TY - JOUR

T1 - Mechanisms of folate cofactors

AU - Benkovic, Stephen J.

AU - Tatum, Charles M.

N1 - Funding Information: This work was supported by research grants AM 09602 from the National Institute ofArthritis, Metabolism and Digestive Diseases, CA 10439 and CA 12226 from the National Cancer Institute, and GM 20594 from National Institute of General Medical Sciences.

PY - 1977/7

Y1 - 1977/7

N2 - Stereospecific isotopic substitution of hydrogen at the bridging carbon in 5,10-methylene tetrahydrofolate promises further insight into stereochemical events at the active site of several folate requiring enzymes.

AB - Stereospecific isotopic substitution of hydrogen at the bridging carbon in 5,10-methylene tetrahydrofolate promises further insight into stereochemical events at the active site of several folate requiring enzymes.

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UR - http://www.scopus.com/inward/citedby.url?scp=49449121003&partnerID=8YFLogxK

U2 - 10.1016/0968-0004(77)90366-8

DO - 10.1016/0968-0004(77)90366-8

M3 - Review article

AN - SCOPUS:49449121003

SN - 0968-0004

VL - 2

SP - 161

EP - 163

JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

IS - 7

ER -

Mechanisms of folate cofactors

Abstract

All Science Journal Classification (ASJC) codes

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