Abstract
The mechanism of suberoylanilide hydroxamic acid in cell growth inhibition involved induction of pRb-2/p130 interaction and nuclear translocation with E2F-4, followed by significant repression in E2F-1 and PCNA nuclear levels, which led to inhibition in DNA synthesis in mammary epithelial cell lines.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 122-133 |
| Number of pages | 12 |
| Journal | Breast Cancer Research |
| Volume | 3 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2001 |
All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research
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