Melatonin secretion after surgery

Arthur J. Cronin; John C. Keifer; Matthew F. Davies; Tonya S. King; Edward O. Bixler

doi:10.1016/S0140-6736(00)02795-1

Melatonin secretion after surgery

Arthur J. Cronin, John C. Keifer, Matthew F. Davies, Tonya S. King, Edward O. Bixler

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114 Scopus citations

Abstract

Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.

Original language	English (US)
Pages (from-to)	1244-1245
Number of pages	2
Journal	Lancet
Volume	356
Issue number	9237
DOIs	https://doi.org/10.1016/S0140-6736(00)02795-1
State	Published - Oct 7 2000

All Science Journal Classification (ASJC) codes

General Medicine

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10.1016/S0140-6736(00)02795-1

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@article{e9eb63d91c8147369913dae2ad3e094b,

title = "Melatonin secretion after surgery",

abstract = "Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.",

author = "Cronin, {Arthur J.} and Keifer, {John C.} and Davies, {Matthew F.} and King, {Tonya S.} and Bixler, {Edward O.}",

note = "Funding Information: This work was supported by the Anesthesia Patient Safety Foundation and the General Clinical Research Center at the Hershey Medical Center (NIH: M01RR10732).",

year = "2000",

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doi = "10.1016/S0140-6736(00)02795-1",

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TY - JOUR

T1 - Melatonin secretion after surgery

AU - Cronin, Arthur J.

AU - Keifer, John C.

AU - Davies, Matthew F.

AU - King, Tonya S.

AU - Bixler, Edward O.

N1 - Funding Information: This work was supported by the Anesthesia Patient Safety Foundation and the General Clinical Research Center at the Hershey Medical Center (NIH: M01RR10732).

PY - 2000/10/7

Y1 - 2000/10/7

N2 - Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.

AB - Sleep disturbance is common postoperatively. We examined whether melatonin concentrations were related to this disturbance in seven postoperative patients. Nocturnal concentrations of melatonin were significantly (p=0.005) lower on the first than on the second or third nights after surgery. This finding raises the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.

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U2 - 10.1016/S0140-6736(00)02795-1

DO - 10.1016/S0140-6736(00)02795-1

M3 - Article

C2 - 11072950

AN - SCOPUS:0034619069

SN - 0140-6736

VL - 356

SP - 1244

EP - 1245

JO - Lancet

JF - Lancet

IS - 9237

ER -

Melatonin secretion after surgery

Abstract

All Science Journal Classification (ASJC) codes

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