TY - GEN
T1 - MEMS device for continuous blood cell separation
AU - Zheng, Siyang
AU - Tai, Yu Chong
AU - Kasdan, Harvey L.
PY - 2005
Y1 - 2005
N2 - New experimental results and theory for a unique MEMS device are presented for continuous, binary separation of erythrocytes (RBC) and leukocytes (WBC) based on particle diameter. Previously, we reported the device can separate 5μm, 8μm and 10μm beads as well as two groups of cells in human blood [1]. In this paper, the critical diameter for separation is successfully predicted with simulation and confirmed with experiment. The separation function (lateral displacement versus particle size) was measured experimentally. Separation of labeled leukocytes confirms the device operation. Combined with previous results, leukocyte separation in single device is demonstrated with 91% efficiency.
AB - New experimental results and theory for a unique MEMS device are presented for continuous, binary separation of erythrocytes (RBC) and leukocytes (WBC) based on particle diameter. Previously, we reported the device can separate 5μm, 8μm and 10μm beads as well as two groups of cells in human blood [1]. In this paper, the critical diameter for separation is successfully predicted with simulation and confirmed with experiment. The separation function (lateral displacement versus particle size) was measured experimentally. Separation of labeled leukocytes confirms the device operation. Combined with previous results, leukocyte separation in single device is demonstrated with 91% efficiency.
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M3 - Conference contribution
AN - SCOPUS:84902458162
SN - 0974361119
SN - 9780974361116
T3 - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 385
EP - 387
BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference
PB - Transducer Research Foundation
T2 - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005
Y2 - 9 October 2005 through 13 October 2005
ER -