Mental health disorders in patients with untreated meningiomas: An observational cohort study using the nationwide marketscan database

Background. Meningiomas are the most common primary tumor of the CNS. Studies investigating the impact of a brain tumor diagnosis on mental health disorders (MHDs) in patients have been limited.The objective of this work is to characterize the incidence and factors affecting the presence of MHDs in untreated meningiomas. Methods. Using a large-scale private payer database, MarketScan, we performed a retrospective study of patients with an untreated meningioma and corresponding MHD. Results. We found that in patients diagnosed with an untreated meningioma, approximately 16% were diagnosed with an MHD within 1 year of the diagnosis of the meningioma. Conclusion. By identifying risk factors, appropriate screening can focus on patients at high-risk for the development of MHD.