Met receptor juxtamembrane exon 14 alternative spliced variant: Novel cancer genomic predictive biomarker

Patrick C. Ma

doi:10.1158/2159-8290.CD-15-0769

Met receptor juxtamembrane exon 14 alternative spliced variant: Novel cancer genomic predictive biomarker

Patrick C. Ma

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Summary: Clinical studies on MET-targeting cancer therapeutics have yielded mixed results in recent years, and MET-relevant predictive biomarkers remain elusive. New studies now reveal MET ex14 alternative splicing aberrations to represent potential predictive cancer genomic biomarker, hence renewing optimism and directions in the quest for optimized MET-targeting personalized cancer therapy.

Original language	English (US)
Pages (from-to)	802-805
Number of pages	4
Journal	Cancer Discovery
Volume	5
Issue number	8
DOIs	https://doi.org/10.1158/2159-8290.CD-15-0769
State	Published - Aug 1 2015

All Science Journal Classification (ASJC) codes

Oncology

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10.1158/2159-8290.CD-15-0769

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title = "Met receptor juxtamembrane exon 14 alternative spliced variant: Novel cancer genomic predictive biomarker",

abstract = "Summary: Clinical studies on MET-targeting cancer therapeutics have yielded mixed results in recent years, and MET-relevant predictive biomarkers remain elusive. New studies now reveal MET ex14 alternative splicing aberrations to represent potential predictive cancer genomic biomarker, hence renewing optimism and directions in the quest for optimized MET-targeting personalized cancer therapy.",

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N2 - Summary: Clinical studies on MET-targeting cancer therapeutics have yielded mixed results in recent years, and MET-relevant predictive biomarkers remain elusive. New studies now reveal MET ex14 alternative splicing aberrations to represent potential predictive cancer genomic biomarker, hence renewing optimism and directions in the quest for optimized MET-targeting personalized cancer therapy.

AB - Summary: Clinical studies on MET-targeting cancer therapeutics have yielded mixed results in recent years, and MET-relevant predictive biomarkers remain elusive. New studies now reveal MET ex14 alternative splicing aberrations to represent potential predictive cancer genomic biomarker, hence renewing optimism and directions in the quest for optimized MET-targeting personalized cancer therapy.

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Met receptor juxtamembrane exon 14 alternative spliced variant: Novel cancer genomic predictive biomarker

Abstract

All Science Journal Classification (ASJC) codes

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