Metabolic activation of benzo[c]phenanthrene by cytochrome P450 enzymes in human liver and lung

Keyphrases

• Metabolic Activation 100%
• Benzo 100%
• Cytochrome P450 Enzymes 100%
• Human Lung 100%
• Phenanthrene 100%
• Human Liver 100%
• Carcinogen 18%
• Human Liver Microsomes 13%
• Rodents 13%
• P450 Enzymes 13%
• Epoxides 9%
• Dihydrodiol 9%
• Genotoxic Metabolites 9%
• Microsomal Preparation 9%
• Polycyclic Aromatic Hydrocarbons 4%
• Tissue Sampling 4%
• Recombinant 4%
• Escherichia Coli 4%
• Catalytic Activity 4%
• Salmonella Enterica Serovar Typhimurium (S. Typhimurium) 4%
• Enzyme Activity 4%
• Selective Inhibitor 4%
• Cytochrome P450 (CYP450) 4%
• Metabolic 4%
• Lung Tissue 4%
• Human Animals 4%
• Experimental Animals 4%
• Rodent Models 4%
• Carcinogenic Polycyclic Aromatic Hydrocarbons 4%
• Biotransformation 4%
• Genotoxic Agents 4%
• P450 4%
• Metabolically Active 4%
• Polycyclic Aromatic Hydrocarbon Metabolites 4%
• LacZ Reporter Gene 4%
• Human Metabolism 4%

Pharmacology, Toxicology and Pharmaceutical Science

• Cytochrome P450 100%
• Phenanthrene 100%
• Carcinogen 18%
• Epoxide 9%
• Polycyclic Aromatic Hydrocarbon 9%
• Salmonella Enterica Serovar Typhimurium 4%
• Escherichia coli 4%
• Experimental Animal 4%
• Recombinant 4%