Metabolomics of sleep disorders in HIV: a narrative review

Monique Balthazar, Idiatou Diallo, Victoria M. Pak

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Purpose: Sleep disturbances are prevalent among patients with human immunodeficiency virus (HIV), even those who are being treated on antiretroviral therapy. It is important to understand the metabolomic mechanisms underlying sleep disturbances among people living with HIV (PLWH). Methods: A review of recent literature was performed to explore the use of metabolomics in understanding sleep among PLWH. Results: We found only two studies that used metabolomics to explore sleep health among PLWH. Conclusion: This paper reviews common sleep disorders in HIV, the existing metabolomic studies that may explain the relationship, and implications for future research. The use of metabolomics in exploring sleep disorders among PLWH will help to elucidate mechanistic links to improve patient outcomes.

Original languageEnglish (US)
Pages (from-to)1333-1337
Number of pages5
JournalSleep and Breathing
Issue number4
StatePublished - Dec 2020

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Clinical Neurology

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