Abstract
The effect of maternally administered methadone hydrochloride (5 mg/kg) on brain development of off-spring treated during gestation and/or lactation was studied in 21-day-old rats. Animals treated during gestation or lactation were the most severely affected, with reductions in brain weights (12% and 30%,respectively), and DNA values (50% and 34%, respectively) observed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1486-1487 |
| Number of pages | 2 |
| Journal | Experientia |
| Volume | 33 |
| Issue number | 11 |
| DOIs | |
| State | Published - Nov 1977 |
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology