Methadone and brain development

I. S. Zagon; Patricia J. McLaughlin

doi:10.1007/BF01918824

Methadone and brain development

I. S. Zagon, Patricia J. McLaughlin

Research output: Contribution to journal › Article › peer-review

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Abstract

The effect of maternally administered methadone hydrochloride (5 mg/kg) on brain development of off-spring treated during gestation and/or lactation was studied in 21-day-old rats. Animals treated during gestation or lactation were the most severely affected, with reductions in brain weights (12% and 30%,respectively), and DNA values (50% and 34%, respectively) observed.

Original language	English (US)
Pages (from-to)	1486-1487
Number of pages	2
Journal	Experientia
Volume	33
Issue number	11
DOIs	https://doi.org/10.1007/BF01918824
State	Published - Nov 1 1977

All Science Journal Classification (ASJC) codes

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/BF01918824

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title = "Methadone and brain development",

abstract = "The effect of maternally administered methadone hydrochloride (5 mg/kg) on brain development of off-spring treated during gestation and/or lactation was studied in 21-day-old rats. Animals treated during gestation or lactation were the most severely affected, with reductions in brain weights (12% and 30%,respectively), and DNA values (50% and 34%, respectively) observed.",

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AB - The effect of maternally administered methadone hydrochloride (5 mg/kg) on brain development of off-spring treated during gestation and/or lactation was studied in 21-day-old rats. Animals treated during gestation or lactation were the most severely affected, with reductions in brain weights (12% and 30%,respectively), and DNA values (50% and 34%, respectively) observed.

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Methadone and brain development

Abstract

All Science Journal Classification (ASJC) codes

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