Methane from acetate

J. G. Ferry

Research output: Contribution to journalShort surveypeer-review

162 Scopus citations


The general features are known for the pathway by which most methane is produced in nature. All acetate-utilizing methanogenic microorganisms contain CODH which catalyzes the cleavage of acetyl-CoA; however, the pathway differs from all other acetate-utilizing anaerobes in that the methyl group is reduced to methane with electrons derived from oxidation of the carbonyl group of acetyl-CoA to CO2. The current understanding of the methanogenic fermentation of acetate provides impressions of nature's novel solutions to problems of methyl transfer, electron transport, and energy conservation. The pathway is now at a level of understanding that will permit productive investigations of these and other interesting questions in the near future.

Original languageEnglish (US)
Pages (from-to)5489-5495
Number of pages7
JournalJournal of bacteriology
Issue number17
StatePublished - 1992

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Molecular Biology


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