MHC polymorphism and human origins

J. Klein; N. Takahata; F. J. Ayala

doi:10.1038/scientificamerican1293-78

MHC polymorphism and human origins

J. Klein, N. Takahata, F. J. Ayala

Biology

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Analysis of the major histocompatibility complex locus, which governs the recognition of self by the immune system, reveals two profound surprises concerning the evolution of humans: the immune system is much older than the species that it protects, and the ancestral population must have been large, not small. There were many Adams and Eves.

Original language	English (US)
Pages (from-to)	78-83+4
Journal	Scientific American
Volume	269
Issue number	6
DOIs	https://doi.org/10.1038/scientificamerican1293-78
State	Published - 1993

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abstract = "Analysis of the major histocompatibility complex locus, which governs the recognition of self by the immune system, reveals two profound surprises concerning the evolution of humans: the immune system is much older than the species that it protects, and the ancestral population must have been large, not small. There were many Adams and Eves.",

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MHC polymorphism and human origins

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