TY - JOUR
T1 - Microbe profile
T2 - Wolbachia: A sex selector, a viral protector and a target to treat filarial nematodes
AU - Taylor, Mark J.
AU - Bordenstein, Seth R.
AU - Slatko, Barton
N1 - Publisher Copyright:
© 2018 The Authors.
PY - 2018/11
Y1 - 2018/11
N2 - Wolbachia is the most widespread genus of endosymbiotic bacteria in the animal world, infecting a diverse range of arthropods and nematodes. A broad spectrum of associations from parasitism to mutualism occur, with a tendency to drive reproductive manipulation or influence host fecundity to spread infection through host populations. These varied effects of Wolbachia are exploited for public health benefits. Notably, the protection of insect hosts from viruses is being tested as a potential control strategy for human arboviruses, and the mutualistic relationship with filarial nematodes makes Wolbachia a target for antibiotic therapy of human and veterinary nematode diseases.
AB - Wolbachia is the most widespread genus of endosymbiotic bacteria in the animal world, infecting a diverse range of arthropods and nematodes. A broad spectrum of associations from parasitism to mutualism occur, with a tendency to drive reproductive manipulation or influence host fecundity to spread infection through host populations. These varied effects of Wolbachia are exploited for public health benefits. Notably, the protection of insect hosts from viruses is being tested as a potential control strategy for human arboviruses, and the mutualistic relationship with filarial nematodes makes Wolbachia a target for antibiotic therapy of human and veterinary nematode diseases.
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U2 - 10.1099/mic.0.000724
DO - 10.1099/mic.0.000724
M3 - Article
C2 - 30311871
AN - SCOPUS:85055844758
SN - 1350-0872
VL - 164
SP - 1345
EP - 1347
JO - Microbiology (United Kingdom)
JF - Microbiology (United Kingdom)
IS - 11
M1 - 000724
ER -