@article{c8b09f0a48274892a607415ccde40682,
title = "Microbial oxidation/amidation of benzhydrylsulfanyl acetic acid. Synthesis of (+)-modafinil",
abstract = "A highly enantioselective oxidation of benzhydrylsulfanyl acetic acid to the corresponding (S)-sulfinyl carboxylic acid was achieved employing the fungus Beauveria bassiana in very good yield. This product was amidated using the bacteria Bacillus subtilis to afford (S)-modafinil in good yield.",
author = "Olivo, {Horacio F.} and Antonio Osorio-Lozada and Peeples, {Tonya L.}",
note = "Funding Information: This research was supported by the National Science Foundation (EEC-0310689). We thank Prof. Jack Rosazza for his invaluable advice and encouragement. We thank Proffers. Rebecca Parales (U California-Davis) and David T. Gibson (U Iowa) for the E. coli NDO and TDO, Prof. Marko Mihovilovic (U Austria) for the E. coli CHMO and CPMO, Prof. Karl-H. Engesser (U Stuttgart) for Sphingomonas sp. HXN-200, and Dr. Kerry O{\textquoteright}Donnell (USDA) for Helminthosporium strains. ",
year = "2005",
month = oct,
day = "31",
doi = "10.1016/j.tetasy.2005.07.028",
language = "English (US)",
volume = "16",
pages = "3507--3511",
journal = "Tetrahedron Asymmetry",
issn = "0957-4166",
publisher = "Elsevier Limited",
number = "21",
}