Abstract
This paper describes microencapsulation of antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, Carmustine) into biodegradable polymer poly(lactic-co-glycolic) acid (PLGA) using an electrojetting technique. The resulting BCNU-loaded PLGA microcapsules have significantly higher drug encapsulation efficiency, more tunable drug loading capacity, and (3) narrower size distribution than those generated using other encapsulation methods.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4555-4560 |
| Number of pages | 6 |
| Journal | Advanced Materials |
| Volume | 25 |
| Issue number | 33 |
| DOIs | |
| State | Published - Sep 6 2013 |
All Science Journal Classification (ASJC) codes
- General Materials Science
- Mechanics of Materials
- Mechanical Engineering
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