TY - GEN
T1 - Microscopic Ultrasound Stimulation of Neural Tissue
AU - Gougheri, Hesam Sadeghi
AU - Kiani, Mehdi
N1 - Publisher Copyright:
© 2018 IEEE.
PY - 2018/12/20
Y1 - 2018/12/20
N2 - Transcranial focused ultrasound has recently been studied as a promising noninvasive neuromodulation technology to stimulate deep brain regions with higher spatial resolution of sub-centimeter (cm) scale, compared with its noninvasive counterparts. In this paper, we propose the concept of microscopic ultrasound stimulation (μUS) in that miniaturized ultrasound transducers can be implanted in the neural (e.g. brain) tissue or on its surface to provide local ultrasound pressure intensities with sub-millimeter (mm) spatial resolution. Using finite-element simulations, we have studied the effects of diameter (0.2-4.5 mm), thickness (0.2-0.5 mm), and sonication frequency (0.5-5 MHz) of a disk-shaped piezoelectric transducer on its resulting acoustic beam profile. Since the focal zone of an ultrasound transducer is scaled down by its size, our results demonstrate the promising spatial resolution of hundreds of micrometers scale using μUS method.
AB - Transcranial focused ultrasound has recently been studied as a promising noninvasive neuromodulation technology to stimulate deep brain regions with higher spatial resolution of sub-centimeter (cm) scale, compared with its noninvasive counterparts. In this paper, we propose the concept of microscopic ultrasound stimulation (μUS) in that miniaturized ultrasound transducers can be implanted in the neural (e.g. brain) tissue or on its surface to provide local ultrasound pressure intensities with sub-millimeter (mm) spatial resolution. Using finite-element simulations, we have studied the effects of diameter (0.2-4.5 mm), thickness (0.2-0.5 mm), and sonication frequency (0.5-5 MHz) of a disk-shaped piezoelectric transducer on its resulting acoustic beam profile. Since the focal zone of an ultrasound transducer is scaled down by its size, our results demonstrate the promising spatial resolution of hundreds of micrometers scale using μUS method.
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U2 - 10.1109/BIOCAS.2018.8584692
DO - 10.1109/BIOCAS.2018.8584692
M3 - Conference contribution
AN - SCOPUS:85060888028
T3 - 2018 IEEE Biomedical Circuits and Systems Conference, BioCAS 2018 - Proceedings
BT - 2018 IEEE Biomedical Circuits and Systems Conference, BioCAS 2018 - Proceedings
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2018 IEEE Biomedical Circuits and Systems Conference, BioCAS 2018
Y2 - 17 October 2018 through 19 October 2018
ER -