Microstructural analysis of porcine skull bone subjected to impact loading

Allison N. Ranslow, Reuben H. Kraft, Ryan Shannon, Patricia De Tomas-Medina, Raul Radovitsky, Aurelie Jean, Martin Pierre Hautefeuille, Brian Fagan, Kimberly A. Ziegler, Tusit Weerasooriya, Ann Mae Dileonardi, Allan Gunnarsson, Sikhanda Satapathy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations


Skull fracture can be a complex process involving various types of bone microstructure. Finite element analysis of the microscopic architecture in the bone allows for a controlled evaluation of the stress wave interactions, micro-crack growth, propagation and eventual coalescence of trabecular fracture. In this paper, the microstructure and mechanics of small-volume sections of a 6-month-old Gottingen Minipig skull were analyzed. MicroCT scans were used to generate finite element models. Various computational methods were investigated for modeling the intricacies contained within the porous microstructure of the trabecular bone. Pores were explicitly meshed in one method, whereas in the second, a mesh was created from a microCT image-informed mapping algorithm that mapped the trabecular porosity from an image stack to a solid volume mesh of the model. From here, all models were subject to uniaxial compression simulations. The output of the simulations allowed for a detailed understanding of the failure mechanics of the skull structure and allowed for comparison between the methods. Fracture typically occurs in the weakest areas where the bone is highly porous and forms a fracture surface throughout the material, which causes the bone to collapse upon itself.

Original languageEnglish (US)
Title of host publicationBiomedical and Biotechnology Engineering
PublisherAmerican Society of Mechanical Engineers (ASME)
ISBN (Electronic)9780791857380
StatePublished - 2015
EventASME 2015 International Mechanical Engineering Congress and Exposition, IMECE 2015 - Houston, United States
Duration: Nov 13 2015Nov 19 2015

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)


OtherASME 2015 International Mechanical Engineering Congress and Exposition, IMECE 2015
Country/TerritoryUnited States

All Science Journal Classification (ASJC) codes

  • Mechanical Engineering


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