Mitotic kinesins: A reason to delve into kinesin-12

William O. Hancock

doi:10.1016/j.cub.2014.09.011

Mitotic kinesins: A reason to delve into kinesin-12

William O. Hancock

Research output: Contribution to journal › Short survey › peer-review

11 Scopus citations

Abstract

The failure of kinesin-targeting cancer drugs is thought to result from functional redundancy of mitotic kinesins. A new study provides mechanistic insights into kinesin-12 that help to explain its targeting to kinetochore fibers and its ability to compensate for inhibition of kinesin-5.

Original language	English (US)
Pages (from-to)	R968-R970
Journal	Current Biology
Volume	24
Issue number	19
DOIs	https://doi.org/10.1016/j.cub.2014.09.011
State	Published - Oct 6 2014

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cub.2014.09.011

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title = "Mitotic kinesins: A reason to delve into kinesin-12",

abstract = "The failure of kinesin-targeting cancer drugs is thought to result from functional redundancy of mitotic kinesins. A new study provides mechanistic insights into kinesin-12 that help to explain its targeting to kinetochore fibers and its ability to compensate for inhibition of kinesin-5.",

author = "Hancock, {William O.}",

year = "2014",

month = oct,

day = "6",

doi = "10.1016/j.cub.2014.09.011",

language = "English (US)",

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TY - JOUR

T1 - Mitotic kinesins

T2 - A reason to delve into kinesin-12

AU - Hancock, William O.

PY - 2014/10/6

Y1 - 2014/10/6

N2 - The failure of kinesin-targeting cancer drugs is thought to result from functional redundancy of mitotic kinesins. A new study provides mechanistic insights into kinesin-12 that help to explain its targeting to kinetochore fibers and its ability to compensate for inhibition of kinesin-5.

AB - The failure of kinesin-targeting cancer drugs is thought to result from functional redundancy of mitotic kinesins. A new study provides mechanistic insights into kinesin-12 that help to explain its targeting to kinetochore fibers and its ability to compensate for inhibition of kinesin-5.

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U2 - 10.1016/j.cub.2014.09.011

DO - 10.1016/j.cub.2014.09.011

M3 - Short survey

C2 - 25291641

AN - SCOPUS:84908208860

SN - 0960-9822

VL - 24

SP - R968-R970

JO - Current Biology

JF - Current Biology

IS - 19

ER -

Mitotic kinesins: A reason to delve into kinesin-12

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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