Mobile DNA in obligate intracellular bacteria

Seth R. Bordenstein, William S. Reznikoff

Research output: Contribution to journalReview articlepeer-review

136 Scopus citations

Abstract

The small genomes of obligate intracellular bacteria are often presumed to be impervious to mobile DNA and the fluid genetic processes that drive diversification in free-living bacteria. Categorized by reductive evolution and streamlining, the genomes of some obligate intracellular bacteria manifest striking degrees of stability and gene synteny. However, recent findings from complete genome sequences of obligate intracellular species and their mobile genetic associates favour the abandonment of these wholesale terms for a more complex and tantalizing picture.

Original languageEnglish (US)
Pages (from-to)688-699
Number of pages12
JournalNature Reviews Microbiology
Volume3
Issue number9
DOIs
StatePublished - Sep 2005

All Science Journal Classification (ASJC) codes

  • Microbiology
  • General Immunology and Microbiology
  • Infectious Diseases

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