Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan

Xichen Lin; Steven M. Weinreb

doi:10.1016/S0040-4039(01)00270-2

Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan

Xichen Lin
, Steven M. Weinreb

Chemistry

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

A chartelline alkaloid model system containing a spirocyclic β-lactam moiety and α,β-unsaturated imine has been constructed from isatin using a Staudinger imine-ketene cycloaddition and an addition to an N-activated γ-lactam as key steps.

Original language	English (US)
Pages (from-to)	2631-2633
Number of pages	3
Journal	Tetrahedron Letters
Volume	42
Issue number	14
DOIs	https://doi.org/10.1016/S0040-4039(01)00270-2
State	Published - Apr 2 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)00270-2

Cite this

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title = "Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan",

abstract = "A chartelline alkaloid model system containing a spirocyclic β-lactam moiety and α,β-unsaturated imine has been constructed from isatin using a Staudinger imine-ketene cycloaddition and an addition to an N-activated γ-lactam as key steps.",

author = "Xichen Lin and Weinreb, \{Steven M.\}",

note = "Funding Information: We are grateful to the National Science Foundation (CHE-97-32038) for financial support of this research. ",

year = "2001",

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doi = "10.1016/S0040-4039(01)00270-2",

language = "English (US)",

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journal = "Tetrahedron Letters",

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T1 - Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan

AU - Lin, Xichen

AU - Weinreb, Steven M.

N1 - Funding Information: We are grateful to the National Science Foundation (CHE-97-32038) for financial support of this research.

PY - 2001/4/2

Y1 - 2001/4/2

N2 - A chartelline alkaloid model system containing a spirocyclic β-lactam moiety and α,β-unsaturated imine has been constructed from isatin using a Staudinger imine-ketene cycloaddition and an addition to an N-activated γ-lactam as key steps.

AB - A chartelline alkaloid model system containing a spirocyclic β-lactam moiety and α,β-unsaturated imine has been constructed from isatin using a Staudinger imine-ketene cycloaddition and an addition to an N-activated γ-lactam as key steps.

UR - https://www.scopus.com/pages/publications/0035795085

UR - https://www.scopus.com/pages/publications/0035795085#tab=citedBy

U2 - 10.1016/S0040-4039(01)00270-2

DO - 10.1016/S0040-4039(01)00270-2

M3 - Article

AN - SCOPUS:0035795085

SN - 0040-4039

VL - 42

SP - 2631

EP - 2633

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 14

ER -

Model studies on total synthesis of the chartellines, spirocyclic β-lactam alkaloids from a marine bryozoan

Abstract

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