TY - JOUR
T1 - Modification of a biventricular assist device to facilitate preservative infusion and organ recovery in a nonheart-beating donor
AU - Angona, Ron
AU - Abt, Peter
AU - Younan, Duraid
AU - Massey, Todd
AU - Marvin, Michael
AU - Kashyap, Randeep
AU - Richards, Dan
AU - Jones, Karen
AU - Queschenbach, James
AU - Zand, Martin
AU - Jain, Ashok
AU - Orloff, Mark
AU - Bozorgzadeh, Adel
PY - 2006/6
Y1 - 2006/6
N2 - A 46-year-old patient supported by a biventricular assist device (BiVAD) was transferred to our institution for evaluation for heart transplant. The patient was found to have a large intracranial hemorrhage with profound deterioration of neurologic status. The poor prognosis prompted the decision to withdraw care and pursue organ donation. Because the patient did not meet brain death criteria, nonheart-beating donor organ donation was pursued. After the termination of care, the BiVAD was modified: the left side to provide organ preservative solution and the right side to allow drainage. Eight liters of cold University of Wisconsin solution were pumped systemically over 10 minutes, the donor was drained, and the liver was harvested. This technique expedited donor perfusion by eliminating the need to cannulate, minimizing ischemic time for the liver. Although the recipient outcome was poor, and retransplantation was eventually necessary, we believe it was most likely not attributable to the quality of organ preservation. This report discusses the technical aspects of this potentially beneficial procedure.
AB - A 46-year-old patient supported by a biventricular assist device (BiVAD) was transferred to our institution for evaluation for heart transplant. The patient was found to have a large intracranial hemorrhage with profound deterioration of neurologic status. The poor prognosis prompted the decision to withdraw care and pursue organ donation. Because the patient did not meet brain death criteria, nonheart-beating donor organ donation was pursued. After the termination of care, the BiVAD was modified: the left side to provide organ preservative solution and the right side to allow drainage. Eight liters of cold University of Wisconsin solution were pumped systemically over 10 minutes, the donor was drained, and the liver was harvested. This technique expedited donor perfusion by eliminating the need to cannulate, minimizing ischemic time for the liver. Although the recipient outcome was poor, and retransplantation was eventually necessary, we believe it was most likely not attributable to the quality of organ preservation. This report discusses the technical aspects of this potentially beneficial procedure.
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M3 - Article
C2 - 16921690
AN - SCOPUS:33749079030
SN - 0022-1058
VL - 38
SP - 157
EP - 160
JO - Journal of Extra-Corporeal Technology
JF - Journal of Extra-Corporeal Technology
IS - 2
ER -