Modified Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy for Hepatoblastoma in a Small Infant

Johnny C. Hong, Joohyun Kim, Meghen Browning, Amy Wagner, Stacee Lerret, Annette D. Segura, Michael A. Zimmerman

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

For patients with hepatoblastoma, a timely and complete resection of the tumor is critical to the patient's tumor recurrence-free survival. Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS), a 2-stage hepatectomy procedure, has revolutionized the surgical management of large hepatic tumors with insufficient future liver remnant (FLR) at presentation. Although existing data support the utility of ALPPS in adults with primary and metastatic hepatobiliary malignancy, the literature in children is scarce. To our knowledge, this is the first report showing clinical applicability and safety of the modified ALPPS procedure in a small infant (54 days old) with hepatoblastoma who presented with insufficient FLR. Our report suggests the modified ALPPS could potentially expand the surgical treatment alternative for small infants with large hepatoblastoma.

Original languageEnglish (US)
Pages (from-to)e16-e17
JournalAnnals of surgery
Volume266
Issue number2
DOIs
StatePublished - Aug 1 2017

All Science Journal Classification (ASJC) codes

  • Surgery

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