TY - JOUR
T1 - Modulated degradation of transient electronic devices through multilayer silk fibroin pockets
AU - Brenckle, Mark A.
AU - Cheng, Huanyu
AU - Hwang, Sukwon
AU - Tao, Hu
AU - Paquette, Mark
AU - Kaplan, David L.
AU - Rogers, John A.
AU - Huang, Yonggang
AU - Omenetto, Fiorenzo G.
N1 - Publisher Copyright:
© 2015 American Chemical Society.
PY - 2015/9/16
Y1 - 2015/9/16
N2 - The recent introduction of transient, bioresorbable electronics into the field of electronic device design offers promise for the areas of medical implants and environmental monitors, where programmed loss of function and environmental resorption are advantageous characteristics. Materials challenges remain, however, in protecting the labile device components from degradation at faster than desirable rates. Here we introduce an indirect passivation strategy for transient electronic devices that consists of encapsulation in multiple air pockets fabricated from silk fibroin. This approach is investigated through the properties of silk as a diffusional barrier to water penetration, coupled with the degradation of magnesium-based devices in humid air. Finally, silk pockets are demonstrated to be useful for controlled modulation of device lifetime. This approach may provide additional future opportunities for silk utility due to the low immunogenicity of the material and its ability to stabilize labile biotherapeutic dopants.
AB - The recent introduction of transient, bioresorbable electronics into the field of electronic device design offers promise for the areas of medical implants and environmental monitors, where programmed loss of function and environmental resorption are advantageous characteristics. Materials challenges remain, however, in protecting the labile device components from degradation at faster than desirable rates. Here we introduce an indirect passivation strategy for transient electronic devices that consists of encapsulation in multiple air pockets fabricated from silk fibroin. This approach is investigated through the properties of silk as a diffusional barrier to water penetration, coupled with the degradation of magnesium-based devices in humid air. Finally, silk pockets are demonstrated to be useful for controlled modulation of device lifetime. This approach may provide additional future opportunities for silk utility due to the low immunogenicity of the material and its ability to stabilize labile biotherapeutic dopants.
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U2 - 10.1021/acsami.5b06059
DO - 10.1021/acsami.5b06059
M3 - Article
C2 - 26305434
AN - SCOPUS:84941781708
SN - 1944-8244
VL - 7
SP - 19870
EP - 19875
JO - ACS Applied Materials and Interfaces
JF - ACS Applied Materials and Interfaces
IS - 36
ER -