Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related zinc-finger ZIM proteins

Hongliu Sun; Brian L. Nelms; Sama F. Sleiman; Helen M. Chamberlin; Wendy Hanna-Rose

doi:10.1534/genetics.107.070847

Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related zinc-finger ZIM proteins

Hongliu Sun, Brian L. Nelms, Sama F. Sleiman, Helen M. Chamberlin, Wendy Hanna-Rose

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The previously reported negative regulatory activity of HIM-8 on the Sox protein EGL-13 is shared by the HIM-8-related ZIM proteins. Furthermore, mutation of HIM-8 can modulate the effects of substitution mutations in the DNA-binding domains of at least four other transcription factors, suggesting broad regulatory activity by HIM-8.

Original language	English (US)
Pages (from-to)	1221-1226
Number of pages	6
Journal	Genetics
Volume	177
Issue number	2
DOIs	https://doi.org/10.1534/genetics.107.070847
State	Published - Oct 2007

All Science Journal Classification (ASJC) codes

Genetics

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10.1534/genetics.107.070847

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title = "Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related zinc-finger ZIM proteins",

abstract = "The previously reported negative regulatory activity of HIM-8 on the Sox protein EGL-13 is shared by the HIM-8-related ZIM proteins. Furthermore, mutation of HIM-8 can modulate the effects of substitution mutations in the DNA-binding domains of at least four other transcription factors, suggesting broad regulatory activity by HIM-8.",

author = "Hongliu Sun and Nelms, {Brian L.} and Sleiman, {Sama F.} and Chamberlin, {Helen M.} and Wendy Hanna-Rose",

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AU - Chamberlin, Helen M.

AU - Hanna-Rose, Wendy

PY - 2007/10

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Modulation of Caenorhabditis elegans transcription factor activity by HIM-8 and the related zinc-finger ZIM proteins

Abstract

All Science Journal Classification (ASJC) codes

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