Abstract
Global dissemination of imipenem-resistant (IR) clones of Acinetobacter baumannii - A. calcoaceticus complex (ABC) have been frequently reported but the molecular epidemiological features of IR-ABC in military treatment facilities (MTFs) have not been described. We characterized 46 IR-ABC strains from a dataset of 298 ABC isolates collected from US service members hospitalized in different US MTFs domestically and overseas during 2003-2008. All IR strains carried the bla OXA-51 gene and 40 also carried bla OXA-23 on plasmids and/or chromosome; one carried bla OXA-58 and four contained ISAbal located upstream of bla OXA-51. Strains tended to cluster by pulsed-field gel electrophoresis profiles in time and location. Strains from two major clusters were identified as international clone I by multilocus sequence typing.
Original language | English (US) |
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Pages (from-to) | 2302-2307 |
Number of pages | 6 |
Journal | Epidemiology and Infection |
Volume | 140 |
Issue number | 12 |
DOIs | |
State | Published - Dec 2012 |
All Science Journal Classification (ASJC) codes
- Epidemiology
- Infectious Diseases