Molecular dynamics simulations reveal structural coordination of Ffh-FtsY heterodimer toward GTPase activation

Keyphrases

• Activated State 10%
• Biochemical Studies 10%
• Catalytic Residues 10%
• Co-translational Protein Targeting 10%
• Complex Associations 10%
• Conformational Change 10%
• Conformational Rearrangement 10%
• Cumulative Energy 10%
• Extended Conformation 10%
• FtsY 100%
• GTPase Signaling 100%
• Guanine 100%
• Hydrolysis 30%
• Interaction Model 10%
• Interaction Network 10%
• Invariant Residues 10%
• Molecular Dynamics Simulation 100%
• Nucleophilic 10%
• Protein Targeting 10%
• Side Chain 10%
• Signal Recognition Particle 50%
• Transition State 10%
• Triphosphate 40%
• Triphosphate Analogues 10%
• Water Molecule 10%

Biochemistry, Genetics and Molecular Biology

• Conformation 10%
• Conformational Change 10%
• Dynamics 10%
• Enzymatic Hydrolysis 40%
• GTPase 100%
• Nucleophilicity 10%
• Protein Targeting 20%
• Signal Recognition Particle 50%
• Triphosphatase 50%