Abstract
Spotting clots: Vascularly constrained colloidal gold nanobeacons (GNBs; see picture) can be used as exogenous photoacoustic contrast agents for the targeted detection of fibrin, a major biochemical feature of thrombus. Fibrin-targeted GNBs provide a more than tenfold signal enhancement in photoacoustic tomography in the near-IR wavelength window, indicating their potential for diagnostic imaging.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 4170-4173 |
| Number of pages | 4 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 48 |
| Issue number | 23 |
| DOIs | |
| State | Published - May 25 2009 |
All Science Journal Classification (ASJC) codes
- Catalysis
- General Chemistry