Morphologies in-between: The impact of the first steps on the human talus

Carla Figus, Nicholas B. Stephens, Rita Sorrentino, Eugenio Bortolini, Simona Arrighi, Owen A. Higgins, Federico Lugli, Giulia Marciani, Gregorio Oxilia, Matteo Romandini, Sara Silvestrini, Fabio Baruffaldi, Maria Giovanna Belcastro, Federico Bernardini, Anna Festa, Tamás Hajdu, Orsolya Mateovics-László, Ildiko Pap, Tamás Szeniczey, Claudio TunizTimothy M. Ryan, Stefano Benazzi

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Objective: The development of bipedalism is a very complex activity that contributes to shaping the anatomy of the foot. The talus, which starts ossifying in utero, may account for the developing stages from the late gestational phase onwards. Here, we explore the early development of the talus in both its internal and external morphology to broaden the knowledge of the anatomical changes that occur during early development. Materials and Methods: The sample consists of high-resolution microCT scans of 28 modern juvenile tali (from 36 prenatal weeks to 2 years), from a broad chronological range from the Late Roman period to the 20th century. We applied geometric morphometric and whole-bone trabecular analysis to investigate the early talar morphological changes. Results: In the youngest group (<6 postnatal months), the immature external shell is accompanied by an isotropic internal structure, with thin and densely packed trabeculae. After the initial attempts of locomotion, bone volume fraction decreases, while anisotropy and trabecular thickness increase. These internal changes correspond to the maturation of the external shell, which is now more defined and shows the development of the articular surfaces. Discussion: The internal and external morphology of the human talus reflects the diverse load on the foot during the initial phases of the bipedal locomotion, with the youngest group potentially reflecting the lack of readiness of the human talus to bear forces and perform bipedal walking. These results highlight the link between mechanical loading and bone development in the human talus during the acquisition of bipedalism, providing new insight into the early phases of talar development.

Original languageEnglish (US)
Pages (from-to)124-142
Number of pages19
JournalAnatomical Record
Volume306
Issue number1
DOIs
StatePublished - Jan 2023

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Biotechnology
  • Anatomy
  • Histology

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