TY - JOUR
T1 - Motor signs distinguish children with high functioning autism and Asperger's syndrome from controls
AU - Jansiewicz, Eva M.
AU - Goldberg, Melissa C.
AU - Newschaffer, Craig J.
AU - Denckla, Martha B.
AU - Landa, Rebecca
AU - Mostofsky, Stewart H.
N1 - Funding Information:
Acknowledgments This study was supported by grants from the National Alliance for Autism Research, the Rita Rudel Foundation, CDC U10/CCU320408 (to CJN) and NIH: K08 NS02039, K02 NS44850, and R01 NS048527 (to SHM), K01MH01824 (to MCG), DAM D17-00-1-0548, P30 HD240614P50, NS 353359, MH 52432R29, and P01 HD35468
PY - 2006/7
Y1 - 2006/7
N2 - While many studies of motor control in autism have focused on specific motor signs, there has been a lack of research examining the complete range of subtle neuromotor signs. This study compared performance on a neurologic examination standardized for children (PANESS, Physical and Neurological Exam for Subtle Signs, Denckla [1974 Developmental Medicine and Child Neurology, 16(6), 729-741]) between a group of 40 boys aged 6-17 with autism and average range IQs and a group of 55 typically developing boys. The Autism group was shown to have significant impairment on several measures of motor control compared to the Control group. Regression analyses revealed that a model including four PANESS variables offered a high level of discrimination in distinguishing boys with high-functioning autism from controls.
AB - While many studies of motor control in autism have focused on specific motor signs, there has been a lack of research examining the complete range of subtle neuromotor signs. This study compared performance on a neurologic examination standardized for children (PANESS, Physical and Neurological Exam for Subtle Signs, Denckla [1974 Developmental Medicine and Child Neurology, 16(6), 729-741]) between a group of 40 boys aged 6-17 with autism and average range IQs and a group of 55 typically developing boys. The Autism group was shown to have significant impairment on several measures of motor control compared to the Control group. Regression analyses revealed that a model including four PANESS variables offered a high level of discrimination in distinguishing boys with high-functioning autism from controls.
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U2 - 10.1007/s10803-006-0109-y
DO - 10.1007/s10803-006-0109-y
M3 - Article
C2 - 16609826
AN - SCOPUS:33745678764
SN - 0162-3257
VL - 36
SP - 613
EP - 621
JO - Journal of Autism and Developmental Disorders
JF - Journal of Autism and Developmental Disorders
IS - 5
ER -