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Keyphrases
Mammalian Target of Rapamycin (mTOR)
100%
Induced Resistance
100%
Methotrexate
100%
B-cell Acute Lymphoblastic Leukemia (B-ALL)
100%
6-mercaptopurine (6-MP)
100%
Ph-like
100%
Dasatinib
85%
MTOR Inhibitor
57%
Cell Cycle Progression
28%
Leukemia Cells
28%
Acute Lymphoblastic Leukemia Cells
28%
Drug Use
14%
Kinase Activity
14%
Cell Death
14%
High Risk
14%
High Incidence
14%
Chemotherapy
14%
Protective Effect
14%
Patient Samples
14%
Poor Prognosis
14%
Chemotherapy Agents
14%
Tyrosine Kinase Inhibitor
14%
Xenograft Model
14%
MTOR Signaling
14%
Cell Cycle Inhibitors
14%
Ongoing Clinical Trials
14%
Chemotherapy Treatment
14%
Standard-of-care Chemotherapies
14%
Signaling Nodes
14%
Aphidicolin
14%
Upstream Signaling
14%
Medicine and Dentistry
Mammalian Target of Rapamycin
100%
Methotrexate
100%
Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase (Ubiquinone)
100%
Acute B-Cell Lymphoblastic Leukemia
100%
Mercaptopurine
100%
Dasatinib
75%
Leukemia Cell
50%
Phosphotransferase
37%
Chemotherapy
37%
B Cell
25%
Mammalian Target of Rapamycin Inhibitor
25%
Acute Lymphoblastic Leukemia
25%
Cell Cycle Progression
25%
Cell Line
12%
Clinical Trial
12%
Cell Death
12%
Cell Cycle
12%
Xenograft
12%
Chemotherapy Agent
12%
Tyrosine-Kinase Inhibitor
12%
Pharmacology, Toxicology and Pharmaceutical Science
Methotrexate
100%
Mercaptopurine
100%
Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase (Ubiquinone)
100%
Acute Lymphoblastic Leukemia
100%
Dasatinib
85%
Chemotherapy Regimens
57%
Phosphotransferase
42%
Leukemia
28%
Mammalian Target of Rapamycin Inhibitor
28%
Clinical Trial
14%
Chemotherapy Agent
14%
Protein Tyrosine Kinase Inhibitor
14%
Palbociclib
14%
Aphidicolin
14%
Biochemistry, Genetics and Molecular Biology
Mammalian Target of Rapamycin
100%
B Cell
100%
Mercaptopurine
100%
Methotrexate
100%
Dasatinib
60%
Kinase
30%
Phosphotransferase
30%
Cell Cycle Progression
20%
Cell Cycle
10%
Cell Death
10%
Clinical Trial
10%
Cell pH
10%
Tyrosine Kinase Inhibitor
10%
Aphidicolin
10%