TY - JOUR
T1 - Mucopurulent cervicitis as a predictor of chlamydial infection and adverse pregnancy outcome
AU - The investigators of the johns hopkins study of cervicitis and adverse pregnancy outcome
AU - Nugent, Robert P.
AU - Hillier, Sharon L.
AU - Polk, B. Frank
AU - Berlin, Linda
AU - Kanchanaraksa, Sukon
AU - Munoz, Alvaro
AU - Kramer, Florence
AU - Spence, Michael
AU - Hoffman, Gary
AU - Winn, Kevin
AU - Repke, John
AU - Jones, M. Douglas
AU - Bartlett, John
AU - Bartlett, John
AU - Laughon, Barbara
AU - Bobo, Linda
AU - Horn, Janet
AU - Kappus, Beth
AU - Mattern, C. F.T.
AU - Brockman, Mary
AU - Donohue, Pam
AU - Lievers, Valerie
AU - Wheeler, Jean
AU - Nugent, Robert
AU - Rhoads, George
PY - 1992
Y1 - 1992
N2 - The role of mucopurulent cervicitis in identifying pregnant women with Chlamydia trachomatis infection and poor pregnancy outcome was examined at the Johns Hopkins Hospital Obstetric Clinic in Baltimore, Maryland. The women studied were at high risk for chlamydial infection (14%), low birth-weight (12%), and preterm delivery (13%). Yellow endocervical discharge on a cotton swab had a sensitivity of 23.9%, specificity of 89.4%, and positive predictive value of 28.6% for predicting chlamydial infection. The presence of ⩾ 30 polymorphonuclear cells per 1000× field had a sensitivity of 25.0%, specificity of 87.6% and positive predictive value of 24.3%. Women with cervicitis defined by ⩾30 polymorphonuclear cells per 1000× field were twice as likely to deliver a low-birthweight infant. Adjustment for potential confounding variables did not explain this association. The poor sensitivity, specificity, and positive predictive value of mucopurulent cervicitis suggests that this parameter is not a useful screening tool for chlamydial infection in pregnant women. However, mucopurulent cervicitis may be an indicator of increased risk for poor pregnancy outcome.
AB - The role of mucopurulent cervicitis in identifying pregnant women with Chlamydia trachomatis infection and poor pregnancy outcome was examined at the Johns Hopkins Hospital Obstetric Clinic in Baltimore, Maryland. The women studied were at high risk for chlamydial infection (14%), low birth-weight (12%), and preterm delivery (13%). Yellow endocervical discharge on a cotton swab had a sensitivity of 23.9%, specificity of 89.4%, and positive predictive value of 28.6% for predicting chlamydial infection. The presence of ⩾ 30 polymorphonuclear cells per 1000× field had a sensitivity of 25.0%, specificity of 87.6% and positive predictive value of 24.3%. Women with cervicitis defined by ⩾30 polymorphonuclear cells per 1000× field were twice as likely to deliver a low-birthweight infant. Adjustment for potential confounding variables did not explain this association. The poor sensitivity, specificity, and positive predictive value of mucopurulent cervicitis suggests that this parameter is not a useful screening tool for chlamydial infection in pregnant women. However, mucopurulent cervicitis may be an indicator of increased risk for poor pregnancy outcome.
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U2 - 10.1097/00007435-199207000-00003
DO - 10.1097/00007435-199207000-00003
M3 - Article
C2 - 1411834
AN - SCOPUS:0026738832
SN - 0148-5717
VL - 19
SP - 198
EP - 202
JO - Sexually transmitted diseases
JF - Sexually transmitted diseases
IS - 4
ER -