Multi-scale Predictions of Drug Resistance Epidemiology Identify Design Principles for Rational Drug Design

Keyphrases

• Biological Evolution 50%
• Biophysical Model 50%
• Breast Cancer 100%
• Clinical Trials 50%
• Design Principles 100%
• Drug Design 50%
• Drug Discovery 50%
• Drug Resistance 100%
• Evolutionary Trajectory 50%
• First-principles Method 50%
• Gastrointestinal Stromal Tumor 50%
• Leukaemia Clinical 50%
• Leukemia 50%
• Meta-analysis 50%
• Most Probable 50%
• Mutational Bias 50%
• Neoadjuvant Setting 50%
• Patient Demographics 50%
• Prostate Cancer 50%
• Rational Drug Design 100%
• Relative Abundance 50%
• Resistance Evolution 50%
• Resistance mutations 100%
• Stochasticity 50%

Biochemistry, Genetics and Molecular Biology

• Clinical Trial 50%
• Drug Resistance 100%
• Evolution 100%