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Mutational load analysis of unrelated individuals
Daniel P Howrigan
, Matthew A Simonson
,
Helen M Kamens
, Sarah H Stephens
, Amanda G Wills
, Marissa A Ehringer
, Matthew C Keller
, Matthew B McQueen
Penn State Cancer Institute
Cancer Institute, Cancer Control
Biobehavioral Health
Penn State Neuroscience Institute
Research output
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peer-review
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Keyphrases
Unrelated Individuals
100%
Minor Allele
100%
Mutational Load
100%
Load Flow Analysis
100%
Overall Effect
60%
Affection
60%
Minor Allele Frequency
40%
Complex Disease
20%
Evolutionary Genetics
20%
Multiple Testing
20%
Nonsynonymous
20%
Genetic Analysis
20%
Significant Genes
20%
Genetic Model
20%
Cumulative Effects
20%
Associated Genes
20%
Functional Single nucleotide Polymorphism
20%
Tiered Approach
20%
Bonferroni Correction
20%
Two-tiered
20%
Whole Exome
20%
Weighting Scheme
20%
Frequency Weighting
20%
Gene Screening
20%
NsSNPs
20%
Deleterious mutations
20%
Biochemistry, Genetics and Molecular Biology
Allele
100%
Mutational Load
100%
Single-Nucleotide Polymorphism
33%
Minor Allele Frequency
33%
Genetics
16%
Evolutionary Genetics
16%
Genetic Model
16%
Exome
16%