N-methoxy-n-methylamides as effective acylating agents

Steven Nahm; Steven M. Weinreb

doi:10.1016/S0040-4039(01)91316-4

N-methoxy-n-methylamides as effective acylating agents

Steven Nahm
, Steven M. Weinreb

Chemistry

Research output: Contribution to journal › Article › peer-review

1875 Scopus citations

Abstract

Readily preparable N-methoxy-N-methylamides couple in good yields with Grignard and organolithium reagents to produce ketones, and are reduced with hydrides to afford aldehydes.

Original language	English (US)
Pages (from-to)	3815-3818
Number of pages	4
Journal	Tetrahedron Letters
Volume	22
Issue number	39
DOIs	https://doi.org/10.1016/S0040-4039(01)91316-4
State	Published - 1981

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)91316-4

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title = "N-methoxy-n-methylamides as effective acylating agents",

abstract = "Readily preparable N-methoxy-N-methylamides couple in good yields with Grignard and organolithium reagents to produce ketones, and are reduced with hydrides to afford aldehydes.",

author = "Steven Nahm and Weinreb, \{Steven M.\}",

year = "1981",

doi = "10.1016/S0040-4039(01)91316-4",

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pages = "3815--3818",

journal = "Tetrahedron Letters",

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T1 - N-methoxy-n-methylamides as effective acylating agents

AU - Nahm, Steven

AU - Weinreb, Steven M.

PY - 1981

Y1 - 1981

N2 - Readily preparable N-methoxy-N-methylamides couple in good yields with Grignard and organolithium reagents to produce ketones, and are reduced with hydrides to afford aldehydes.

AB - Readily preparable N-methoxy-N-methylamides couple in good yields with Grignard and organolithium reagents to produce ketones, and are reduced with hydrides to afford aldehydes.

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UR - https://www.scopus.com/pages/publications/27844466269#tab=citedBy

U2 - 10.1016/S0040-4039(01)91316-4

DO - 10.1016/S0040-4039(01)91316-4

M3 - Article

AN - SCOPUS:27844466269

SN - 0040-4039

VL - 22

SP - 3815

EP - 3818

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 39

ER -

N-methoxy-n-methylamides as effective acylating agents

Abstract

All Science Journal Classification (ASJC) codes

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