TY - JOUR
T1 - Nano-enabled delivery of intracellular therapeutics
AU - Ostadhossein, Fatemeh
AU - Daza, Enrique Alejandro
AU - Frankowski, Daniel
AU - Goatz, Drew
AU - Imgruet, Molly
AU - Kus, Joseph
AU - Lake, Ryan
AU - Modak, Mallika
AU - Olsen, Nick
AU - Schwartz-Duval, Aaron
AU - Zimmer, Alyssa
AU - Kolmodin, Nicholas
AU - Pan, Dipanjan
N1 - Publisher Copyright:
© Springer International Publishing Switzerland 2015.
PY - 2016/6/1
Y1 - 2016/6/1
N2 - Many diseases that plague the modern medical world have their origins at the cellular or molecular level and, as such, require greater specificity to be effectively combated and cured. A number of recent advances in understanding the biology and biochemistry have enabled researchers to develop the specialized tools and techniques needed to detect and provide therapy for these debilitating conditions. Many of these treatments take advantage of the way that cells behave and interact with their environment or various properties of the cell’s structure and form. Researchers are able to surpass a number of cellular hurdles, such as the cell membrane, endosomal escape, and intracellular targeting to begin the arduous task of understanding, diagnosing, and treating diseases like cancer.
AB - Many diseases that plague the modern medical world have their origins at the cellular or molecular level and, as such, require greater specificity to be effectively combated and cured. A number of recent advances in understanding the biology and biochemistry have enabled researchers to develop the specialized tools and techniques needed to detect and provide therapy for these debilitating conditions. Many of these treatments take advantage of the way that cells behave and interact with their environment or various properties of the cell’s structure and form. Researchers are able to surpass a number of cellular hurdles, such as the cell membrane, endosomal escape, and intracellular targeting to begin the arduous task of understanding, diagnosing, and treating diseases like cancer.
UR - http://www.scopus.com/inward/record.url?scp=84975879585&partnerID=8YFLogxK
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U2 - 10.1007/7355_2015_97
DO - 10.1007/7355_2015_97
M3 - Article
AN - SCOPUS:84975879585
SN - 1862-2461
VL - 20
SP - 105
EP - 120
JO - Topics in Medicinal Chemistry
JF - Topics in Medicinal Chemistry
ER -