TY - GEN
T1 - Nano-patterned bacterial cellulose hydrogel exhibits bactericidal activity against e. Coli and k. pneumoniae
AU - Arias, Sandra L.
AU - Cheng, Ming Kit
AU - Civantos, Ana
AU - Devorkin, Joshua
AU - Jaramillo, Camilo
AU - Allain, Jean Paul
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Statement of Purpose: Biomedical devices are at risk of infections by microbial contamination during surgery, by hematogenous dissemination of bacteria from infections elsewhere in the body, or by the entrance of bacteria through body orifices in contact with biomaterials1. Once on the surface, bacteria aggregate into biofilms leading to severe complications that compromise biomaterial function and patient morbidity. Biofilms are difficult to eradicate by conventional systemic antibiotic therapy, while other strategies such as chemical modification of the material surface with biocidal compounds and delivery of nanoparticles at the infected site, can induce multidrug-resistant strains and produce a toxic accumulation of unwanted products in other tissues, respectively2.
AB - Statement of Purpose: Biomedical devices are at risk of infections by microbial contamination during surgery, by hematogenous dissemination of bacteria from infections elsewhere in the body, or by the entrance of bacteria through body orifices in contact with biomaterials1. Once on the surface, bacteria aggregate into biofilms leading to severe complications that compromise biomaterial function and patient morbidity. Biofilms are difficult to eradicate by conventional systemic antibiotic therapy, while other strategies such as chemical modification of the material surface with biocidal compounds and delivery of nanoparticles at the infected site, can induce multidrug-resistant strains and produce a toxic accumulation of unwanted products in other tissues, respectively2.
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UR - http://www.scopus.com/inward/citedby.url?scp=85065432329&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85065432329
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -