Nanogel carrier for intracellular delivery of quantum dot

Urara Hasegawa, Kazunari Akiyoshi

Research output: Contribution to conferencePaperpeer-review


We report here a novel carrier for intracellular delivery of quantum dots (QDs). Monodisperse hybrid nanoparticles (38 nm in diameter) were prepared by simple mixing of quantum dots and nanogels of cholesterol-bearing pullulan (CHP) modified with amino groups (CHPNH 2). These nanoparticles were immediately adsorbed on to cell surface and effectively internalized into cells. The efficiency of cellular uptake was much higher than that of cationic liposome. In additon, the internalization of QDs with cells was controlled by the amino-group content of CHPNH 2 nanogel. These hybrid nanoparticles could be utilized as a novel fluorescent probe for bioimaging.

Original languageEnglish (US)
Number of pages2
StatePublished - 2005
Event54th SPSJ Symposium on Macromolecules - Yamagata, Japan
Duration: Sep 20 2005Sep 22 2005


Conference54th SPSJ Symposium on Macromolecules

All Science Journal Classification (ASJC) codes

  • General Engineering


Dive into the research topics of 'Nanogel carrier for intracellular delivery of quantum dot'. Together they form a unique fingerprint.

Cite this