Abstract
The science of 'theranostics plays a crucial role in personalized medicine, which represents the future of patient management. Over the last decade an increasing research effort has focused on the development of nanoparticle-based molecular-imaging and drug-delivery approaches, emerging as a multidisciplinary field that shows promise in understanding the components, processes, dynamics and therapies of a disease at a molecular level. The potential of nanometer-sized agents for early detection, diagnosis and personalized treatment of diseases is extraordinary. They have found applications in almost all clinically relevant biomedical imaging modality. In this review, a number of these approaches will be presented with a particular emphasis on MRI and optical imaging-based techniques. We have discussed both established molecular-imaging approaches and recently developed innovative strategies, highlighting the seminal studies and a number of successful examples of theranostic nanomedicine, especially in the areas of cardiovascular and cancer therapy.
Original language | English (US) |
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Pages (from-to) | 471-490 |
Number of pages | 20 |
Journal | Future Medicinal Chemistry |
Volume | 2 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2010 |
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Pharmacology
- Drug Discovery