@inproceedings{5c647e9999a94cc489421f73ba2c9cbe,
title = "Nanopore Digital Counting of Amplicons for Ultrasensitive Electronic DNA Detection",
abstract = "We demonstrate the feasibility of using the single molecule sensing nanopore as a digital counter to enumerate the amplicons for ultrasensitive electronic nucleic acid analysis. We show that the nanopore digital counting approach could capture the DNA replication dynamics in the LAMP reaction and has the potential to be used in a qualitative test as well as in a quantitative test. By keeping nanopores as simple as possible and by leveraging the amplification assay's high sensitivity, the amplification-coupled nanopore digital counting approach provides a promising optics-free method for highly sensitive and specific nucleic acid testing.",
author = "Zifan Tang and Gihoon Choi and Reza Nouri and Weihua Guan",
note = "Funding Information: This work supported by the National Science Foundation under Grant No. 1710831 and 1912410. Publisher Copyright: {\textcopyright} 2019 IEEE.; 65th Annual IEEE International Electron Devices Meeting, IEDM 2019 ; Conference date: 07-12-2019 Through 11-12-2019",
year = "2019",
month = dec,
doi = "10.1109/IEDM19573.2019.8993671",
language = "English (US)",
series = "Technical Digest - International Electron Devices Meeting, IEDM",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
booktitle = "2019 IEEE International Electron Devices Meeting, IEDM 2019",
address = "United States",
}