Nanostructured microfluidic digestion system for rapid high-performance proteolysis

Gong Cheng; Si Jie Hao; Xu Yu; Si Yang Zheng

doi:10.1039/c4lc01165a

Nanostructured microfluidic digestion system for rapid high-performance proteolysis

Gong Cheng, Si Jie Hao, Xu Yu, Si Yang Zheng

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.

Original language	English (US)
Pages (from-to)	650-654
Number of pages	5
Journal	Lab on a Chip
Volume	15
Issue number	3
DOIs	https://doi.org/10.1039/c4lc01165a
State	Published - Feb 7 2015

All Science Journal Classification (ASJC) codes

Bioengineering
Biochemistry
General Chemistry
Biomedical Engineering

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10.1039/c4lc01165a

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title = "Nanostructured microfluidic digestion system for rapid high-performance proteolysis",

abstract = "A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.",

author = "Gong Cheng and Hao, {Si Jie} and Xu Yu and Zheng, {Si Yang}",

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AU - Cheng, Gong

AU - Hao, Si Jie

AU - Yu, Xu

AU - Zheng, Si Yang

N1 - Publisher Copyright: © The Royal Society of Chemistry 2015.

PY - 2015/2/7

Y1 - 2015/2/7

N2 - A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.

AB - A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.

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Nanostructured microfluidic digestion system for rapid high-performance proteolysis

Abstract

All Science Journal Classification (ASJC) codes

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