TY - JOUR
T1 - Naproxen-induced thrombocytopenia
AU - Sahu, Nitasa
AU - Roy, Justin
AU - Vunnam, Rama
AU - Golamari, Reshma
AU - Jain, Rohit
N1 - Publisher Copyright:
© Copyright © 2020 Baylor University Medical Center.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Thrombocytopenia has many mechanisms with broad differentials. A detailed history and physical, with timely diagnostic testing, is necessary to parse out the underlying etiology. Clinicians should maintain a high suspicion for drug-induced thrombocytopenia when there is an acute drop in the platelet level after exposure to commonly implicated drugs. Drug-induced thrombocytopenia is not well defined, as reporting is voluntary and not critically reviewed. Oftentimes, the culprit is not the drug itself, but a drug metabolite, which is difficult to prove with drug-dependent antibody testing. Here we present a case where naproxen led to hemarthrosis secondary to drug-induced thrombocytopenia.
AB - Thrombocytopenia has many mechanisms with broad differentials. A detailed history and physical, with timely diagnostic testing, is necessary to parse out the underlying etiology. Clinicians should maintain a high suspicion for drug-induced thrombocytopenia when there is an acute drop in the platelet level after exposure to commonly implicated drugs. Drug-induced thrombocytopenia is not well defined, as reporting is voluntary and not critically reviewed. Oftentimes, the culprit is not the drug itself, but a drug metabolite, which is difficult to prove with drug-dependent antibody testing. Here we present a case where naproxen led to hemarthrosis secondary to drug-induced thrombocytopenia.
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U2 - 10.1080/08998280.2020.1798724
DO - 10.1080/08998280.2020.1798724
M3 - Article
C2 - 33100559
AN - SCOPUS:85088982485
SN - 0899-8280
VL - 33
SP - 653
EP - 654
JO - Baylor University Medical Center Proceedings
JF - Baylor University Medical Center Proceedings
IS - 4
ER -