Nasal radioiodine activity: A prospective study of frequency, intensity, and pattern

E. H. Norby, Janet Neutze, D. Van Nostrand, K. D. Burman, R. W. Warren

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23 Scopus citations


The nose has been reported as a site of radioiodine accumulation on 131I whole-body scintigraphy. To determine the frequency, intensity, and pattern of nasal radioiodine accumulation, a prospective study was performed on 21 patients referred for 131I whole-body scintigraphy during a 26-mo interval. All patients were dosed with 5 mCi (18.5 MBq) of 131I p.o., and imaged 72 hr later. Ninety-five percent (20/21) of patients had nasal radioactivity greater than background, and in 75% (15/20) of positive patients the pattern of activity was round. Clinical follow-up of these patients has shown no evidence of tumor involvement in the nasal area. We conclude that nasal radioiodine activity is a normal finding. Radioiodine uptake in the nasal area, without clinical suspicion of metastatic disease should not be considered a criterion for surgical intervention or radioiodine therapy.

Original languageEnglish (US)
Pages (from-to)52-54
Number of pages3
JournalJournal of Nuclear Medicine
Issue number1
StatePublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging


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