Nearest neural neighbors: Moth sex pheromone receptors HR11 and HR13

Thomas C. Baker

Research output: Contribution to journalComment/debatepeer-review

19 Scopus citations


In moth sex pheromone olfaction systems, there is a stereotypical cocompartmentalization of two or sometimes three olfactory receptor neurons (ORNs) within single trichoid sensilla on which pheromone-sensitive odorant receptors (ORs) are differentially expressed. In this issue of Chemical Senses, Krieger et al. show through elegant double and triple in situ hybridization studies that in the moth, Heliothis virescens, a pheromone component-related OR (HR11) is expressed on an ORN that is reliably cocompartmentalized in the same sensillum as another OR (HR13) whose ligand is known to be (Z)-11-hexadecenal, the H. virescens major pheromone component. Although the ligand for HR11 is not yet known, mapping this OR to this particular ORN represents a key advance in piecing together the puzzle of H. virescens sex pheromone olfaction.

Original languageEnglish (US)
Pages (from-to)465-468
Number of pages4
JournalChemical senses
Issue number6
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Physiology
  • Sensory Systems
  • Physiology (medical)
  • Behavioral Neuroscience


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