Necrotizing Soft Tissue Infections of the Perineum

Bryan P. Kline, Nimalan A. Jeganathan

Research output: Contribution to journalArticlepeer-review


Necrotizing soft tissue infections of the perineum are rapidly progressing infections associated with significant morbidity and mortality. Prompt diagnosis and management with early surgical debridement is necessary to improve survival from this deadly disease. Repeat debridements are not uncommon. Important adjuncts to surgery include broad-spectrum antibiotics and management in an intensive care unit, as patients frequently develop multisystem organ failure. Once the acute phase is managed, fecal diversion with either an ostomy or fecal management catheter can be considered to decrease soiling of the wound and facilitate healing. Long-term management requires meticulous wound care, often with the assistance of negative pressure wound therapy. Patients may ultimately require skin grafts or tissue flaps for soft tissue coverage following extensive surgical debridements.

Original languageEnglish (US)
Pages (from-to)237-243
Number of pages7
JournalClinics in Colon and Rectal Surgery
Issue number3
StatePublished - May 1 2022

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology


Dive into the research topics of 'Necrotizing Soft Tissue Infections of the Perineum'. Together they form a unique fingerprint.

Cite this