Neural networks for emergent behavior in biological microstructures

Purpose: This paper develops a neural network surrogate model based on a discrete lattice approach to investigate the influence of complex microstructures on the emergent behavior of biological networks. Design/methodology/approach: The adaptability of network-forming organisms, such as, slime molds, relies on fluid-to-solid state transitions and dynamic behaviors at the level of the discrete microstructure, which continuum modeling methods struggle to capture effectively. To address this challenge, we present an optimized approach that combines lattice spring modeling with machine learning to capture dynamic behavior and develop nonlinear constitutive relationships. Findings: This integrated approach allows us to predict the dynamic response of biological materials with heterogeneous microstructures, overcoming the limitations of conventional trial-and-error lattice design. The study investigates the microstructural behavior of biological materials using a neural network-based surrogate model. The results indicate that our surrogate model is effective in capturing the behavior of discrete lattice microstructures in biological materials. Research limitations/implications: The combination of numerical simulations and machine learning endows simulations of the slime mold Physarum polycephalum with a more accurate description of its emergent behavior and offers a pathway for the development of more effective lattice structures across a wide range of applications. Originality/value: The novelty of this research lies in integrating lattice spring modeling and machine learning to explore the dynamic behavior of biological materials. This combined approach surpasses conventional methods, providing a more holistic and accurate representation of emergent behaviors in organisms.