Neuroendocrine Aspects of Chronic Fatigue Syndrome

Dimitris A. Papanicolaou, Jay D. Amsterdam, Susan Levine, Samuel M. McCann, Rebecca C. Moore, Clare H. Newbrand, Glen Allen, Rosane Nisenbaum, Donald W. Pfaff, George C. Tsokos, Alexandros Vgontzas, Anthony Kales

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations


Chronic fatigue syndrome (CFS) is a serious health concern affecting over 800,000 Americans of all ages, races, socioeconomic groups and genders. The etiology and pathophysiology of CFS are unknown, yet studies have suggested an involvement of the neuroendocrine system. A symposium was organized in March 2001 to explore the possibility of an association between neuroendocrine dysfunction and CFS, with special emphasis on the interactions between neuroendocrine dysfunction and other abnormalities noted in the immune and autonomic nervous systems of individuals with CFS. This paper represents the consensus of the panel of experts who participated in this meeting.

Original languageEnglish (US)
Pages (from-to)65-74
Number of pages10
Issue number2
StatePublished - 2004

All Science Journal Classification (ASJC) codes

  • Immunology
  • Endocrinology
  • Neurology
  • Endocrine and Autonomic Systems


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