Neuroendocrine, Psychophysiological and Subjective Reactivity to an Alcohol Placebo in Male Alcoholic Patients

Zelig S. Dolinsky; David E. Morse; Richard F. Kaplan; Roger E. Meyer; Douglas Corry; Ovide F. Pomerleau

doi:10.1111/j.1530-0277.1987.tb01311.x

Neuroendocrine, Psychophysiological and Subjective Reactivity to an Alcohol Placebo in Male Alcoholic Patients

Zelig S. Dolinsky, David E. Morse, Richard F. Kaplan, Roger E. Meyer, Douglas Corry, Ovide F. Pomerleau

Department of Psychiatry and Behavioral Health

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Alteration in neuroendocrine activity associated with the regulation of energy metabolism and food intake may play a role in characterizing the alcohol dependent state. Alcoholics, when compared to controls, demonstrated significantly larger and more rapid glucose and insulin responses following the consumption of a placebo beer, which they believed contained alcohol. The existence of significant correlations between peak neuroendocrine responses and desire to drink, anxiety, as well as psychophysiological responses in alcoholics suggests the potential multivariate nature of the biological/behavioral state associated with alcohol dependence.

Original language	English (US)
Pages (from-to)	296-300
Number of pages	5
Journal	Alcoholism: Clinical and Experimental Research
Volume	11
Issue number	3
DOIs	https://doi.org/10.1111/j.1530-0277.1987.tb01311.x
State	Published - Jun 1987

All Science Journal Classification (ASJC) codes

Medicine (miscellaneous)
Toxicology
Psychiatry and Mental health

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10.1111/j.1530-0277.1987.tb01311.x

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title = "Neuroendocrine, Psychophysiological and Subjective Reactivity to an Alcohol Placebo in Male Alcoholic Patients",

abstract = "Alteration in neuroendocrine activity associated with the regulation of energy metabolism and food intake may play a role in characterizing the alcohol dependent state. Alcoholics, when compared to controls, demonstrated significantly larger and more rapid glucose and insulin responses following the consumption of a placebo beer, which they believed contained alcohol. The existence of significant correlations between peak neuroendocrine responses and desire to drink, anxiety, as well as psychophysiological responses in alcoholics suggests the potential multivariate nature of the biological/behavioral state associated with alcohol dependence.",

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AU - Morse, David E.

AU - Kaplan, Richard F.

AU - Meyer, Roger E.

AU - Corry, Douglas

AU - Pomerleau, Ovide F.

PY - 1987/6

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AB - Alteration in neuroendocrine activity associated with the regulation of energy metabolism and food intake may play a role in characterizing the alcohol dependent state. Alcoholics, when compared to controls, demonstrated significantly larger and more rapid glucose and insulin responses following the consumption of a placebo beer, which they believed contained alcohol. The existence of significant correlations between peak neuroendocrine responses and desire to drink, anxiety, as well as psychophysiological responses in alcoholics suggests the potential multivariate nature of the biological/behavioral state associated with alcohol dependence.

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Neuroendocrine, Psychophysiological and Subjective Reactivity to an Alcohol Placebo in Male Alcoholic Patients

Abstract

All Science Journal Classification (ASJC) codes

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