Nitrogen balance in patients treated with extracorporeal membrane oxygenation

Thomas R. Weber, Manoj Shah, Cindy Stephens, Tom Tracy

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Extracorporeal membrane oxygenation (ECMO) is a commonly used technique in the management of newborn respiratory failure. However, few studies have addressed the optimal nutritional support of these critically ill neonates. Eleven newborns undergoing ECMO for respiratory failure were studied at various levels of intravenous caloric and nitrogen intake, using nitrogen balance techniques, to assess optimal nutritional support necessary to achieve positive nitrogen balance. Nonprotein nitrogen calories > 60 kcal/kg/d, and nitrogen > 240 mg/kg/d were necessary to achieve positive nitrogen balance, while maximum positive balance was seen with nitrogen intake > 400 mg/kg/d. These data suggest that newborns treated with ECMO can achieve positive nitrogen balance with modest amounts of caloric and nitrogen intake.

Original languageEnglish (US)
Pages (from-to)906-908
Number of pages3
JournalJournal of pediatric surgery
Issue number7
StatePublished - Jul 1993

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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