NK cell receptors in antiviral immunity

Janice M. Moser; Anthony M. Byers; Aron E. Lukacher

doi:10.1016/S0952-7915(02)00357-6

NK cell receptors in antiviral immunity

Janice M. Moser, Anthony M. Byers, Aron E. Lukacher

Research output: Contribution to journal › Review article › peer-review

34 Scopus citations

Abstract

An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8⁺ αβ T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8⁺ T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.

Original language	English (US)
Pages (from-to)	509-516
Number of pages	8
Journal	Current Opinion in Immunology
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/S0952-7915(02)00357-6
State	Published - Aug 1 2002

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology

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10.1016/S0952-7915(02)00357-6

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title = "NK cell receptors in antiviral immunity",

abstract = "An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8+ T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.",

author = "Moser, {Janice M.} and Byers, {Anthony M.} and Lukacher, {Aron E.}",

note = "Funding Information: The authors would like to thank Peter Jensen, Taku Kambayashi, Erika Assarsson and Erin Buckingham for helpful discussions and comments on the manuscript. This work was supported by National Institutes of Health grant CA71971. ",

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T1 - NK cell receptors in antiviral immunity

AU - Moser, Janice M.

AU - Byers, Anthony M.

AU - Lukacher, Aron E.

N1 - Funding Information: The authors would like to thank Peter Jensen, Taku Kambayashi, Erika Assarsson and Erin Buckingham for helpful discussions and comments on the manuscript. This work was supported by National Institutes of Health grant CA71971.

PY - 2002/8/1

Y1 - 2002/8/1

N2 - An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8+ T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.

AB - An array of inhibitory and activating receptors initially identified on NK cells are also expressed by conventional CD8+ αβ T cells. New evidence strongly implicates these 'NK cell receptors' in modulating NK cell and virus-specific CD8+ T cell responses against a variety of viral infections. Precise regulation of NK cell and T cell responses by these receptors optimizes antiviral immunity while preventing immunological bystander pathology and autoimmunity.

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U2 - 10.1016/S0952-7915(02)00357-6

DO - 10.1016/S0952-7915(02)00357-6

M3 - Review article

C2 - 12088687

AN - SCOPUS:0036668254

SN - 0952-7915

VL - 14

SP - 509

EP - 516

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

IS - 4

ER -

NK cell receptors in antiviral immunity

Abstract

All Science Journal Classification (ASJC) codes

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