NMR-Based Metabolomics in Cancer Research

Rui Hu; Tao Li; Yunhuang Yang; Yuan Tian; Limin Zhang

doi:10.1007/978-3-030-51652-9_14

NMR-Based Metabolomics in Cancer Research

Rui Hu, Tao Li, Yunhuang Yang, Yuan Tian, Limin Zhang

Huck Institutes of the Life Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter

8 Scopus citations

Abstract

Nuclear magnetic resonance (NMR) spectroscopy offers reproducible quantitative analysis and structural identification of metabolites in various complex biological samples, such as biofluids (plasma, serum, and urine), cells, tissue extracts, and even intact organs. Therefore, NMR-based metabolomics, a mainstream metabolomic platform, has been extensively applied in many research fields, including pharmacology, toxicology, pathophysiology, nutritional intervention, disease diagnosis/prognosis, and microbiology. In particular, NMR-based metabolomics has been successfully used for cancer research to investigate cancer metabolism and identify biomarker and therapeutic targets. This chapter highlights the innovations and challenges of NMR-based metabolomics platform and its applications in cancer research.

Original language	English (US)
Title of host publication	Advances in Experimental Medicine and Biology
Publisher	Springer
Pages	201-218
Number of pages	18
DOIs	https://doi.org/10.1007/978-3-030-51652-9_14
State	Published - 2021

Publication series

Name	Advances in Experimental Medicine and Biology
Volume	1280
ISSN (Print)	0065-2598
ISSN (Electronic)	2214-8019

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1007/978-3-030-51652-9_14

Cite this

@inbook{eecda17b8865410691878571cc2742cb,

title = "NMR-Based Metabolomics in Cancer Research",

abstract = "Nuclear magnetic resonance (NMR) spectroscopy offers reproducible quantitative analysis and structural identification of metabolites in various complex biological samples, such as biofluids (plasma, serum, and urine), cells, tissue extracts, and even intact organs. Therefore, NMR-based metabolomics, a mainstream metabolomic platform, has been extensively applied in many research fields, including pharmacology, toxicology, pathophysiology, nutritional intervention, disease diagnosis/prognosis, and microbiology. In particular, NMR-based metabolomics has been successfully used for cancer research to investigate cancer metabolism and identify biomarker and therapeutic targets. This chapter highlights the innovations and challenges of NMR-based metabolomics platform and its applications in cancer research.",

author = "Rui Hu and Tao Li and Yunhuang Yang and Yuan Tian and Limin Zhang",

note = "Publisher Copyright: {\textcopyright} 2021, Springer Nature Switzerland AG.",

year = "2021",

doi = "10.1007/978-3-030-51652-9_14",

language = "English (US)",

series = "Advances in Experimental Medicine and Biology",

publisher = "Springer",

pages = "201--218",

booktitle = "Advances in Experimental Medicine and Biology",

}

TY - CHAP

T1 - NMR-Based Metabolomics in Cancer Research

AU - Hu, Rui

AU - Li, Tao

AU - Yang, Yunhuang

AU - Tian, Yuan

AU - Zhang, Limin

PY - 2021

Y1 - 2021

N2 - Nuclear magnetic resonance (NMR) spectroscopy offers reproducible quantitative analysis and structural identification of metabolites in various complex biological samples, such as biofluids (plasma, serum, and urine), cells, tissue extracts, and even intact organs. Therefore, NMR-based metabolomics, a mainstream metabolomic platform, has been extensively applied in many research fields, including pharmacology, toxicology, pathophysiology, nutritional intervention, disease diagnosis/prognosis, and microbiology. In particular, NMR-based metabolomics has been successfully used for cancer research to investigate cancer metabolism and identify biomarker and therapeutic targets. This chapter highlights the innovations and challenges of NMR-based metabolomics platform and its applications in cancer research.

AB - Nuclear magnetic resonance (NMR) spectroscopy offers reproducible quantitative analysis and structural identification of metabolites in various complex biological samples, such as biofluids (plasma, serum, and urine), cells, tissue extracts, and even intact organs. Therefore, NMR-based metabolomics, a mainstream metabolomic platform, has been extensively applied in many research fields, including pharmacology, toxicology, pathophysiology, nutritional intervention, disease diagnosis/prognosis, and microbiology. In particular, NMR-based metabolomics has been successfully used for cancer research to investigate cancer metabolism and identify biomarker and therapeutic targets. This chapter highlights the innovations and challenges of NMR-based metabolomics platform and its applications in cancer research.

UR - http://www.scopus.com/inward/record.url?scp=85103654133&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85103654133&partnerID=8YFLogxK

U2 - 10.1007/978-3-030-51652-9_14

DO - 10.1007/978-3-030-51652-9_14

M3 - Chapter

C2 - 33791984

AN - SCOPUS:85103654133

T3 - Advances in Experimental Medicine and Biology

SP - 201

EP - 218

BT - Advances in Experimental Medicine and Biology

PB - Springer

ER -

NMR-Based Metabolomics in Cancer Research

Abstract

Publication series

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this