Non-invasive optical assessment of intracranial pressure: Pilot results in human patients

Wesley B. Baker, Tracy M. Flanders, Ramani Balu, Lian He, Kristina Heye, Elizabeth Mahanna Gabrielli, John J. Flibotte, Daniel J. Licht, Gregory G. Heuer, Arjun G. Yodh, W. Andrew Kofke

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We present pilot results on the validation of non-invasive assessment of elevated intracranial pressure with optical measurement of critical closing pressure. A strong correlation (r=0.85) between optical measurements of critical closing pressure and invasive measurements of intracranial pressure was observed in 5 infants with hydrocephalus, and 1 adult patient with diffuse hypoxic ischemic brain injury. By facilitating timely detection of intracranial hypertension, this approach has potential to reduce risk of brain damage in hydrocephalus and other vulnerable patient populations.

Original languageEnglish (US)
Title of host publicationDiffuse Optical Spectroscopy and Imaging VII
EditorsHamid Dehghani, Heidrun Wabnitz
PublisherSPIE
ISBN (Electronic)9781510628410
DOIs
StatePublished - 2019
EventDiffuse Optical Spectroscopy and Imaging VII 2019 - Munich, Germany
Duration: Jun 23 2019Jun 25 2019

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume11074
ISSN (Print)1605-7422

Conference

ConferenceDiffuse Optical Spectroscopy and Imaging VII 2019
Country/TerritoryGermany
CityMunich
Period6/23/196/25/19

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging
  • Biomaterials

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